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factor VII

   Also found in: Dictionary/thesaurus, Medical, Legal, Financial, Wikipedia, Hutchinson 0.03 sec.
factor VII [′fak·tər ′se·vən]
(biochemistry)
A procoagulant, related to prothrombin, that is involved in the formation of a prothrombin-converting principle which transforms prothrombin to thrombin. Also known as stable factor.


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Mayer and a team of physicians in North America, Europe, Asia, and Australia treated 303 bleeding-stroke patients with an intravenous drug called recombinant activated factor VII (rFVIIa), which certain hemophilia patients receive under the brand name NovoSeven.
Another patient, a 28-year-old man, had been diagnosed with a factor VII deficiency (activity: 20%) during childhood, but he did not undergo detailed analysis or experience any post-tonsillectomy bleeding.
People with high levels of fibrinogen and activated factor VII have a higher risk of heart attacks.
 
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