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factor XI

   Also found in: Dictionary/thesaurus, Medical, Legal, Financial, Acronyms, Wikipedia 0.01 sec.
factor XI [′fak·tər ə′le·vən]
(biochemistry)
A procoagulant present in normal blood but deficient in hemophiliacs. Also known as plasma thromboplastin antecedent (PTA).


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There are three types of hemophilia - Hemophilia A, which is caused by non-functioning clotting Factor VII, is the most common; Hemophilia B is caused by non-functioning clotting Factor IX; and Hemophilia C, which is caused by non-functioning clotting Factor XI.
Though thrombotic events have been commonly reported with factor XI and factor VIII concentrates, it is an unusual complication after administration of DDAVP alone in a patient with VWD.
AF253319), choriogenin 2 (E = 1e-45), choriogenin 3 (E = 4e-43), coagulation factor XI (E = 3e-12), ER[alpha] (E = 1e-71), glycosylate reductase (E = 3e-14), hepatic lipase precursor (E = 7e-6), 3-hydroxy-3-methylglutaryl-coenzyme A (CoA) reductase (E = 9e-51), low-molecular-mass protein 2 (E = 2e-12), transferrin (E = 8e-26), ubiquitin-conjugating enzyme 9 (the cDNA clone is 87% identical at the 5' end to an EST clone (GenBank accession no.
 
 
 
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