Say, in the first "generation" of research, the false-positive rate
The reason this apparent false-positive rate
from this study is so high is mostly because the Kepler team has been very generous with the last few data releases with what has been called a 'candidate'," Morton says.
The test correctly identifies about 80 percent of women who are carrying a baby with Down syndrome and has a false-positive rate
of about five percent.
Yet knowledge of the false-positive rate
is not sufficient to determine a test's usefulness, as the above HIV test example illustrates.
They also expressed concerns about the high false-positive rate
The current prenatal screening standard of care for Down syndrome and other trisomies in low-risk pregnancies is more than three times as likely to return a false positive, compared with false-positive rates
from noninvasive, cell-free DNA testing, according to a new study.
The XE 2100 presented the largest changes in review rate, false-negative rate, and false-positive rate
according to changes in the cutoff values of quantitative flags.
After distributing the unknowns by the observed ratios of objects, the team arrived at the 35 percent false-positive rate
Sensitivity was defined as the percentage of positive examinations among women diagnosed with breast cancer, and the false-positive rate
as the percentage of positive examinations among women without a breast cancer diagnosis.
The results of the analysis showed that contingent screening had a detection rate of 93%, with a false-positive rate
of 4% in a relative comparison of the three methods for detection of trisomy 21 in the FASTER population.
So, for example, if using maternal age alone is compared with using maternal age plus AFP/ HCG/uE3, the detection rate increases from about 49% to 78% and the false-positive rate
drops from about 13% to 8%.
Outcomes measured The authors reported the sensitivity and false-positive rate
of the integrated test and compared them with characteristics of the existing screening strategies.