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The infection of humans with Fasciola hepatica.



a helminthiasis of animals and man; one of the trematodiases. It is caused by the common liver fluke and giant liver fluke, which parasitize man, cattle, sheep, swine, and other animals. The eggs are deposited mainly in the bile ducts of the liver and gall-bladder and are later excreted with the feces. The flukes continue their cycle of development in water and in snails, their intermediate hosts. Infection occurs when the larvae are swallowed with water and plants. In man, a fever develops within two to four weeks, together with a cough and skin eruptions. The liver enlarges and becomes tender. Acute manifestations gradually subside and the disease becomes chronic, a condition marked chiefly by digestive disorders and enlargement and tenderness of the liver.

Fascioliasis of animals occurs worldwide and may be acute or chronic. In the USSR it affects cattle and other bovines and camels, horses, and hares. The animals are infected in pastures. Hepatitis develops and results in impaired metabolism. The parasites’ toxins alter the morphological and chemical composition of the blood. Infected animals manifest loss of appetite, diarrhea, debilitation, and liver enlargement. Milk secretion is reduced in cows. In sheep, severe infestation is fatal.

In man, fascioliasis is treated with Chloxyl or emetine; in animals it is treated with Hexychol, bithionol, or carbon tetrachloride. The disease is prevented in man by boiling or filtering drinking water. It is prevented in animals by changing pastures, exterminating snails, and carrying out other sanitary measures.


Skriabin, K. I. Trematody zhivotnykh i cheloveka, vol. 2. Moscow-Leningrad, 1948.
Demidov, N. V. Fastsiolez zhivotnykh. Moscow, 1965.


References in periodicals archive ?
hepatica IgG ELISA test evaluated here, are presently available for the diagnosis of animal fascioliasis.
Key words: Fascioliasis, epidemiology, slaughter house, economic losses, bovines
The findings in this case are most likely explained by TCBZ resistance, although we note that repeated TCBZ courses are not 100% effective against fascioliasis (6).
Fascioliasis and other plant-borne trematode zoonoses.
Review by Chen and Mott 1990 was the first paper to highlight the importance of human fascioliasis as a public health issue.
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Differential diagnoses, including human fascioliasis, toxocara visceral larva migrans, ectopic biliary ascaris, chronic eosinophilic leukaemia (CEL) and hypereosinophilic syndrome (HES), were considered.
The fascioliasis also affects different blood parameters in the infected animals that are important for the diagnosis of the disease.
La fascioliasis es una entidad a considerar en el diagnostico diferencial con las colecistitis, sobre todo alitiasicas.
Fascioliasis was defined as a positive Fasciola immunofluorescent antibody test with a screening titer of 1:32 and either compatible clinical or radiologic features consistent with the disease.
Aspectos epidemiologicos de la fascioliasis bovina en el Centra Occidente Venezolano con enfasis en la prevalencia del trematode y de su hospedador intermediario.