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The infection of humans with Fasciola hepatica.



a helminthiasis of animals and man; one of the trematodiases. It is caused by the common liver fluke and giant liver fluke, which parasitize man, cattle, sheep, swine, and other animals. The eggs are deposited mainly in the bile ducts of the liver and gall-bladder and are later excreted with the feces. The flukes continue their cycle of development in water and in snails, their intermediate hosts. Infection occurs when the larvae are swallowed with water and plants. In man, a fever develops within two to four weeks, together with a cough and skin eruptions. The liver enlarges and becomes tender. Acute manifestations gradually subside and the disease becomes chronic, a condition marked chiefly by digestive disorders and enlargement and tenderness of the liver.

Fascioliasis of animals occurs worldwide and may be acute or chronic. In the USSR it affects cattle and other bovines and camels, horses, and hares. The animals are infected in pastures. Hepatitis develops and results in impaired metabolism. The parasites’ toxins alter the morphological and chemical composition of the blood. Infected animals manifest loss of appetite, diarrhea, debilitation, and liver enlargement. Milk secretion is reduced in cows. In sheep, severe infestation is fatal.

In man, fascioliasis is treated with Chloxyl or emetine; in animals it is treated with Hexychol, bithionol, or carbon tetrachloride. The disease is prevented in man by boiling or filtering drinking water. It is prevented in animals by changing pastures, exterminating snails, and carrying out other sanitary measures.


Skriabin, K. I. Trematody zhivotnykh i cheloveka, vol. 2. Moscow-Leningrad, 1948.
Demidov, N. V. Fastsiolez zhivotnykh. Moscow, 1965.


References in periodicals archive ?
Keywords: Fasciolosis, Small ruminants; Altitudes; Azad Jammu and Kashmir;
De igual forma, en una finca en Siquirres de Limon, otros investigadores encontraron que durante agosto de 2005 a agosto de 2006, la prevalencia de fasciolosis determinada por la presencia de huevecillos en heces, fue del 11,3% (3).
Cundinamarca cuenta las resenas mas antiguas y numerosas del pais sobre fasciolosis bovina y humana; sin embargo, gran parte del departamento esta por investigar.
Por lo reportado por otras investigaciones hechas en el pais y la experiencia de veterinarios oficiales de SENASA y regentes en los mataderos, la infeccion por este parasito parece no ser homogenea en el pais; es por esto que la prevalencia obtenida a partir del analisis global de los sacrificios y decomisos totales en uno o varios establecimientos, sin considerar la region geografica de la que procede la res, es probable que sea menor a la presente en las zonas donde la fasciolosis es endemica.
Considering that knowledge of the time of occurrence of mollusc is most important for the establishment of control programs for fasciolosis, and the population studies of the intermediate hosts contribute to the knowledge of the ecology of these, the aim of this study was to monitor the population density of L.
An early diagnosis and treatment with newer drugs for fasciolosis in goats could be advised to reduce economic losses due to better efficacy on fasciolosis in goats.
Todo ello es determinante para que las especies rumiantes entren en el ciclo biologico de la fasciolosis hepatica y actuen como diseminadores de huevos embrionados, que al hallar a un ambiente humedo encuentra condiciones favorables para la persistencia de la parasitosis.
La vacunacion es vista como una alternativa no quimica para el control de la fasciolosis (Dalton y Mulcahy, 2001; Smith, 1999).
Important economic losses associated with fasciolosis are: great expenses on anthelmintics for treatment; liver condemnation; production loss due to mortality; lower production of meat, milk and wool; reduced weight gain; metabolic diseases and impaired fertility [6,7].
Chronic fasciolosis is associated with mature flukes, and seen mainly in late winter/ early spring.
Some aspects of the epidemiology of bovine fasciolosis in northern Gazira and Khartoum State.
Para la valoracion de los anticuerpos se siguio las instrucciones del kit Porquier[R] ELISA de verificacion de fasciolosis bovina en suero y leche, version P05120/04 [17].