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The infection of humans with Fasciola hepatica.



a helminthiasis of animals and man; one of the trematodiases. It is caused by the common liver fluke and giant liver fluke, which parasitize man, cattle, sheep, swine, and other animals. The eggs are deposited mainly in the bile ducts of the liver and gall-bladder and are later excreted with the feces. The flukes continue their cycle of development in water and in snails, their intermediate hosts. Infection occurs when the larvae are swallowed with water and plants. In man, a fever develops within two to four weeks, together with a cough and skin eruptions. The liver enlarges and becomes tender. Acute manifestations gradually subside and the disease becomes chronic, a condition marked chiefly by digestive disorders and enlargement and tenderness of the liver.

Fascioliasis of animals occurs worldwide and may be acute or chronic. In the USSR it affects cattle and other bovines and camels, horses, and hares. The animals are infected in pastures. Hepatitis develops and results in impaired metabolism. The parasites’ toxins alter the morphological and chemical composition of the blood. Infected animals manifest loss of appetite, diarrhea, debilitation, and liver enlargement. Milk secretion is reduced in cows. In sheep, severe infestation is fatal.

In man, fascioliasis is treated with Chloxyl or emetine; in animals it is treated with Hexychol, bithionol, or carbon tetrachloride. The disease is prevented in man by boiling or filtering drinking water. It is prevented in animals by changing pastures, exterminating snails, and carrying out other sanitary measures.


Skriabin, K. I. Trematody zhivotnykh i cheloveka, vol. 2. Moscow-Leningrad, 1948.
Demidov, N. V. Fastsiolez zhivotnykh. Moscow, 1965.


References in periodicals archive ?
Important economic losses associated with fasciolosis are: great expenses on anthelmintics for treatment; liver condemnation; production loss due to mortality; lower production of meat, milk and wool; reduced weight gain; metabolic diseases and impaired fertility [6,7].
Cases of human fasciolosis are said to be on the increase since the 1980's.
The AHVLA data is backed by reports from vets, who have found a growing number of fasciolosis cases at postmortem examinations.
Comparison of adult somatic and cysteine proteinase antigens of Fasciola gigantica in enzyme linked immunosorbent assay for serodiagnosis of human fasciolosis.
gigantica were involved in both ruminant and human Fasciolosis.
Evidence suggesting that Fasciola gigantica may be the most prevalent causal agent of Fasciolosis in Northern Iran.
Palabras clave: novillo, fasciolosis, dano hepatico, hematologia, bioquimica.
The objective of the trial was to investigate eventual changes of hepatic damage blood indicators, during the subclinical (asymptomatic) period of fasciolosis.
In Corrientes, fasciolosis has been known to affect cattle and sheep for a long time.
En la decada de 1990 se introdujeron bufalos en zonas de esteros y bailados y en el ano 2000 se reportan los primeros casos de fasciolosis en esa especie (12).
The purpose of the study was to determine the prevalence of the fluke Fasciola hepatica in capybaras (Hydrochaeris hydrochaeris) from Corrientes, Argentina, for its possible role in the epizootiology of hepatic fasciolosis in other possible hosts.
En la Provincia de Corrientes, como en otros lugares de Argentina, Fasciola hepatica es bien conocida por causar una enfermedad parasitaria en los rumiantes, la fasciolosis, responsable de cuantiosas perdidas economicas de la ganaderia (14).