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fetal hemoglobin

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fetal hemoglobin [′fēd·əl ′hē·mə‚glō·bən]
(biochemistry)
A normal embryonic hemoglobin having alpha chains identical to those of normal adult human hemoglobin, and gamma chains similar to adult beta chains.


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The presence of fetal hemoglobin (HbF) seems to protect babies and younger children from problems of ACS; as hemoglobin F declined with age, risk for ACS increases.
Neonates and fetuses are more vulnerable because of the natural leftward shift of the dissociation curve of fetal hemoglobin, a lower baseline [P.
6) Infant s and neonates are more susceptible to the development of methemoglobinemia, because fetal hemoglobin is less resistant to oxidant stresses than adult hemoglobin and the enzymatic pathways for the conversion of metHb back to hemoglobin are somewhat deficient in the neonatal period.
 
 
 
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