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Fibrosarcoma

   Also found in: Medical, Wikipedia 0.01 sec.
fibrosarcoma [¦fī·brō·sär′kō·mə]
(medicine)
A sarcoma composed of spindle cells that produce collagenous fibrils.

Fibrosarcoma 

an immature malignant tumor of connective tissue; a malignant variant of fibroma, fibromyoma (leiomyoma), or fibroadenoma that can occur in any part of the body. It is characterized by invasive and destructive growth but sometimes has distinct contours. In cross section it looks like fish flesh. A fibrosarcoma has a marked capacity to metastasize, chiefly through blood vessels. It can often be distinguished from a fibroma only by histological examination and is treated surgically.



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There are 4 types of spindle cell sarcoma: undifferentiated sarcoma of bone, malignant fibrous histiocytoma, fibrosarcoma and leiomyosarcoma.
Other areas discussed include brachytherapy and cryoblation for soft tissue sarcomas, gastrointestinal stromal tumors, Kaposi's sarcoma progression and regression, and expression of COL1A1-PDGFB fusion transcripts in superficial adult fibrosarcoma.
The researchers have already fused a variant of diphtheria toxin into the Rad51 gene as a "toxic bomb" and tested it on a variety of cancer cell types, including breast cancer, fibrosarcoma, and cervical cancer cells.
 
 
 
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