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fibrosarcoma

   Also found in: Medical, Wikipedia 0.03 sec.
fibrosarcoma [¦fī·brō·sär′kō·mə]
(medicine)
A sarcoma composed of spindle cells that produce collagenous fibrils.


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The histologic differential diagnosis is predicated on whether the tumor is biphasic or monophasic; it includes adenocarcinoma, spindle cell carcinoma, fibrosarcoma, malignant peripheral nerve sheath tumor, glomangiopericytoma (hemangiopericytoma), leiomyosarcoma, malignant melanoma, epithelioid sarcoma, and angiosarcoma.
Seeking an explanation, Jian-Wei Gu and his colleagues at the University of Mississippi Medical Center in Jackson inoculated chick embryos with human fibrosarcoma cells, derived from a type of bone cancer.
In this new study titled Prevention of inflammation-mediated acquisition of metastatic properties of benign mouse fibrosarcoma cells by administration of an orally available superoxide dismutase, published in the British Journal of Cancer (2006), SOD/gliadin was shown to prevent the progression of tumors that are influenced by oxidative stress and inflammation in mice.
 
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