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fibrosarcoma |
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fibrosarcoma [¦fī·brō·sär′kō·mə] (medicine) A sarcoma composed of spindle cells that produce collagenous fibrils. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Narrower fascicular bundles and a herringbone pattern are more typical of tumors formerly considered to be fibrosarcomas. 13,14) Specific IHC stains, especially desmin, have helped to improve the accuracy of diagnosis and differentiate LMS from other mesodermal tumors, such as fibromas, fibrosarcomas, spindle-cell sarcomas, rhabdomyosarcoma, malignant melanomas, and inflammatory myofibroblastic tumors. Although S-100 protein can be positive in 10% to 20% of fibrosarcomas, the additional presence of neurofilaments and glial fibrillary acidic protein excluded such a diagnosis. |
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