fibrosis

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Related to fibrotic: fibrinous, fibrosis, fibrotic myopathy

fibrosis

the formation of an abnormal amount of fibrous tissue in an organ or part as the result of inflammation, irritation, or healing

fibrosis

[fī′brō·səs]
(medicine)
Growth of fibrous connective tissue in an organ or part in excess of that naturally present.
References in periodicals archive ?
In this study, we analyzed the expression pattern of TAZ in both cellular and fibrotic NSIP.
While they address some of the inflammation that occurs in this disease, they fail to target the fibrotic process itself.
The decision follows the successful filing of a US Investigational New Drug application for AVB-S6-500, a novel GAS6-AXL pathway inhibitor which Aravive is developing for the treatment of cancer and non-malignant fibrotic conditions.
It is a specific type of interstitial lung disease in which the small air sacs of the lung, the "alveoli," gradually become replaced by fibrotic (scar) tissue and is the cause of worsening dyspnea (shortness of breath).
Histopathological study revealed widely hyalinized fibrotic tissue with spotty hyalinizing necrosis infiltrating adipose tissue and striated muscle tissue (Figures 2a, 2b).
Its portfolio of integrin antagonists has potential utility in a broad range of fibrotic diseases.
With the strong strategic fit between our companies, we intend to continue to move PRM-151 forward rapidly as a new treatment option to address the unmet needs of patients with myelofibrosis, idiopathic pulmonary fibrosis, and other fibrotic diseases.
We hypothesized that for those ears showing a fibrotic tissue link to the ossicles, the CC threshold will be lower than that for BC at frequencies below 2.
The study discovered that a molecule on these cells is a key regulator of fibrotic disease.
At time of laparotomy, she was found to have a Meckel's diverticulum without intussusception, but with a dense fibrotic reaction of the mesentery and total obstruction.
Chronic exposure to inorganic dusts can result in a fibrotic process in the lung parenchyma.
Such high numbers of crosslinks are characteristic of "changes we see in humans with fibrotic lung disease,' Last says.