fluorination


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fluorination

[‚flu̇r·ə′nā·shən]
(chemistry)
A chemical reaction in which fluorine is introduced into a chemical compound.
References in periodicals archive ?
X, "Surface Modification of Fluoroelastomer by Direct Fluorination with Fluorine Gas.
16]O determinations for whole rock samples were carried out by laser fluorination using a conventional vacuum extraction line employing ClF3 as the reagent (Borthwick and Harmon, 1982; Clayton and Mayeda, 1963).
They also have considerable experience in fluorination chemistry, successfully synthesising multiple (poly)fluorinated target molecules utilising a range of methods of fluorine introduction and exploiting the altered chemical reactivity of the substrates in the downstream chemistry.
Inside medicinal and synthetic chemistry themselves, I'd suggest thinking of better ways to do the things we already know are valuable: fluorination for making things more metabolically stable, to pick one, alternatives to basic tertiary amines when you run into hERG channel and potential cardiovascular problems, good general ways to make compounds more soluble and easier to formulate (and good reactions to accomplish these things).
Electrophilic fluorination using the Selectfluor" reagent was accomplished at two different points in the synthetic scheme, affording ring-selective fluorine incorporation into the sulfanilamide targets in yields ranging from 40-82%.
Originally developed for dermatologic applications, the molecule derives its potency from fluorination at the C6 and C9 positions.
Sirona will be responsible for the chemistry, using its proprietary expertise in fluorination technology.
Under the contract, Sirona will be responsible for the chemistry, using its proprietary expertise in fluorination technology, while Bloom Burton will be responsible for financing, clinical validation and commercialisation of the compounds.
Topics covered include ring synthesis, substituent installation and modification, reduction to partially hydrogenated pyridines, piperidines, and quinolines, alkaloid synthesis, fluorination, and the use of pyridines as reagents.
Meng, LY, Park, Si, "Effect of Fluorination of Carbon Nanotubes on Superhydrophobic Properties of Fluoro-Based Films.
Laser fluorination revealed that its ratio of heavier-to-lighter oxygen isotopes, usually a handy fingerprint of a meteorite's origins, didn't match any of the Mars meteorites described in the scientific literature.