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Prozac
(redirected from fluoxetine)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
Prozac, trade name for fluoxetine hydrochloride. See antidepressant antidepressant, any of a wide range of drugs used to treat psychic depression. They are given to elevate mood, counter suicidal thoughts, and increase the effectiveness of psychotherapy.
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Prozac

First of the class of antidepressant drugs called selective serotonin reuptake inhibitors (SSRIs), generic name fluoxetine hydrochloride. Introduced in 1986 as a treatment for clinical depression, Prozac is also used to treat a variety of other psychiatric disorders, including obsessive-compulsive disorder and bulimia nervosa. The drug, taken as a pill, apparently achieves its therapeutic effect by interfering with the reabsorption of the neurotransmitter serotonin within the brain.


Prozac
™ fluoxetine; a drug that prolongs the action of serotonin in the brain; used as an antidepressant


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Approval of the combination antipsychotic / antidepressant was based on data from five trials demonstrating statistically significant reductions in mean total Montgomery-Asberg Depression Rating Scale (MADRS) scores relative to either fluoxetine alone or olanzapine alone among patients who met DSM-IV criteria for major depressive disorder (MDD) and who previously did not respond to two antidepressants of adequate dose and duration.
The pattern they saw from the trial results of fluoxetine (Prozac), paroxetine (Seroxat), venlafaxine (Effexor) and nefazodone (Serzone) was consistent.
Fluoxetine is also used to treat many other conditions, such as ADHD.
 
 
 
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