galactosidase


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galactosidase

[gə‚lak·tə′sī‚dās]
(biochemistry)
An enzyme that hydrolyzes galactosides.
References in periodicals archive ?
NYSE AMEX: IBIO) today announced the engagement of CBR International Corporation (CBR) for strategic regulatory and clinical services to advance iBio's Orphan Drug designated, plant-produced human alpha galactosidase A ("-Gal A") enzyme candidate for development as a therapeutic option for patients with Fabry disease.
NYSE AMEX:IBIO) today announced it has acquired Orphan Drug Designation for plant-produced human alpha galactosidase A ("-Gal A") and related property rights from an affiliate of Kentucky Bioprocessing LLC ("KBP") and has initiated a program, based on its iBioLaunch[TM] platform, to develop an improved version of the enzyme for therapy of Fabry disease.
They are interested in techniques which allow the splitting of lactose by means of galactosidase into two other sugars: glucose and galactose.
The investigators sequenced and removed seven genes for the galactose-removing enzyme beta galactosidase.
Sufferers of this genetic disorder have reduced or deficient galactosidase activity.
Amigal is designed to selectively bind to and stabilize alpha- galactosidase A (alpha-GAL), the enzyme deficient in Fabry disease.
Beano is the only over-the- counter natural dietary supplement brand that contains the enzyme, alpha- galactosidase, which according to a recently published professional paper all Americans lack to varying degrees(4).
Amicus' technology represents a unique approach to treating the enzyme deficiency (alpha galactosidase A) that characterizes Fabry disease.