In soil studies at the Delaware Biotechnology Institute, a premier center for life sciences research at UD, the scientists discovered that invasive Phragmites produces elevated levels of a benign compound, a precursor of gallic acid known as gallotannin
, relative to its native cousin.
Determination of GalloTannin
content in fermented Rice bran by HPLC Sample Preparation
The major commercial application of this enzyme is in the hydrolysis of gallotannin
to gallic acid, which is an intermediate required for the synthesis of an antifolic antibacterial drug trimethoprim (Sitting et al.
, one of tea's components is thought to be up to 1000 times more effective than existing medicines in the treatment of brain damage in stroke patients.
13]C NMR and mass spectral analysis and based on the spectral data it was identified as a well-known gallotannin
compound 1,2,3,4,6 penta-0-galloy1-[beta]-D-glucose and based on the in vitro findings the PGG was further evaluated for ex vivo 11[beta]-HSD-1 inhibition activity and against HFD-induced diabetes in C57BL/6 mice.
The EA-7/8-9/10-4 fraction was evolved as a most potent fraction among all the fractions and it was identified as well known gallotannin
compound 1,2,3,4,6 penta-O-galloyl- [beta]-D-glucose (PGG) by spectral analysis.
1) is a gallotannin
identified in several plants, including Phyllanthus urinaria (Hau et al.
Insulinomimetic activity of two new gallotannins
from the fruits of Capparis moonii.
, including cornusiens-A to -G, tellimagrandin I and II, camptothins-A and -B;
In their research, the scientists extracted gallotannins
from mango kernels with aqueous acetone.
Although more studies are needed, the scientists concluded that mangoes' anti-cancer benefits can be attributed to gallotannins
, a class of polyphenols that target, in a natural way, cells on the verge of mutation by disrupting their division cycle.
The anticancer potential of berries has been related, at least in part, to a multitude of bioactive phytochemicals that these colorful fruits contain, including polyphenols (flavonoids, proanthocyanidins, ellagitannins, gallotannins
, phenolic acids), stilbenoids, lignans, and triterpenoids.