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gastrin |
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gastrin [′gas·trən] (biochemistry) A polypeptide hormone secreted by the pyloric mucosa which stimulates the pancreas to release pancreatic fluid and the stomach to release gastric acid. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Six of the mice lacking gastrin developed stomach tumors at 12 months of age, but none of normal mice did, the researchers report in the March 31 Oncogene. Aphton's anti-gastrin targeted therapy induces antibodies in patients that bind to both gastrin 17 and gly-gastrin and remove them from circulation before they can bind to the cancer cell and initiate cell growth. They secrete a substance called gastrin that causes the stomach to produce too much acid, which in turn causes the stomach and duodenal ulcers (peptic ulcers). |
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