gelatinase


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gelatinase

[′jel·ə·tə‚nās]
(biochemistry)
An enzyme, found in some yeasts and molds, that liquefies gelatin.
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Incidence of hemolysin, gelatinase, and aggregation substance among enterococci isolated from patients with endocarditis and other infections and from feces of hospitalized and community-based persons.
There is initial, usually asymptomatic colonization of gastrointestinal tract by enterococcal strains possessing various traits, such as antibiotic resistances, cytolytic toxin genes, or possibly aggregation substance or the protease gelatinase upon hospital admission (59).
The interplay of collagen IV, tumor necrosis factor-[alpha], gelatinase B (matrix metalloprotease-9), and tissue inhibitor of metalloproteases-1 in the basal lamina regulates Sertoli cell-tight junction dynamics in the rat testis," Endocrinology 144(1): 371-387.
This drug has been shown to have in vitro activity against collagenase and gelatinase, and in animal studies it reduced the severity of OA.
We sought to compare the temporal changes in extracellular matrix activities such as proteoglycan synthesis, glycosaminoglycan accumulation, and gelatinase activity that occur in the cervix before, during, and after delivery, so as to precisely define the biochemical events orchestrating the matrix remodeling.
Tumors use this particular enzyme, gelatinase, to initiate angiogenesis.
Lipocalin2 also known as neutrophil gelatinase associated lipocalin, sidrocalin and 24p3, is another member of the lipocalin family recently reported to have possible metabolic roles [7].
Results showed that all the isolates (VP1-VP3 and VR1-VR3) produced P-hemolysis on rabbit blood agar, lecithinase, proteinase, and gelatinase, but DNase and lipase were not produced.
Gelatinase activity was detected as clear zones of lysis (negative staining) against the blue background.
It was positive for ornithine decarboxylase, gelatinase, reduction of nitrates to nitrites, tolerance to 6% NaCl, and assimilation of caprate and malate, but negative for citrate utilization, arginine dihydrolase, lysine decarboxylase, urease, indole production, assimilation of mannose, glucose, arabinose, mannitol, maltose, adipate, and acidification of glucose.