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general paresis

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
general paresis [¦jen·rəl pə′rē·səs]
(medicine)
An inflammatory and degenerative disease of the brain caused by infection withTreponema pallidum. Also known as syphilitic meningoencephalitis.


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Among their cases are a comparison two cases of 19th-century general paresis in Guy de Maupassant and Friedrich Nietzsche, substance abuse versus epilepsy in Edgar Allan Poe, Immanuel Kant's evolution from a personality disorder to a dementia, bipolar disorder as an explanation of Van Gogh's night, the terminal illness and last compositions of Maurice Ravel, Georg Friedrich Handel's strokes, and music and brain in Gershwin and Shebalin.
14) Common MRI findings in neurosyphilis patients with general paresis (personality [paranoia, carelessness in appearance]; affect [labile]; reflexes [hyperactive]; eye [Argyll Robertson pupils]; sensorium [hallucinations, illusions, delusions]; intellect [decreased recent memory, judgment, insight]; and speech [slurred]) include dilated ventricles and either increased signal or atrophy of the medial temporal lobes.
 
 
 
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