general paresis


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general paresis

[¦jen·rəl pə′rē·səs]
(medicine)
An inflammatory and degenerative disease of the brain caused by infection with Treponema pallidum. Also known as syphilitic meningoencephalitis.
References in periodicals archive ?
Among their cases are a comparison two cases of 19th-century general paresis in Guy de Maupassant and Friedrich Nietzsche, substance abuse versus epilepsy in Edgar Allan Poe, Immanuel Kant's evolution from a personality disorder to a dementia, bipolar disorder as an explanation of Van Gogh's night, the terminal illness and last compositions of Maurice Ravel, Georg Friedrich Handel's strokes, and music and brain in Gershwin and Shebalin.
14) Common MRI findings in neurosyphilis patients with general paresis (personality [paranoia, carelessness in appearance]; affect [labile]; reflexes [hyperactive]; eye [Argyll Robertson pupils]; sensorium [hallucinations, illusions, delusions]; intellect [decreased recent memory, judgment, insight]; and speech [slurred]) include dilated ventricles and either increased signal or atrophy of the medial temporal lobes.
On the other hand, we are presented with excerpts from letters of Nietzsche's which already manifest mental illness (most likely general paresis insanity) as if they were revelatory of crucial issues in his philosophy (pp.