genomic imprinting


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genomic imprinting

[jə¦nō·mik im‚print·iŋ]
(genetics)
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But while such applications should prove a boon to geneticists and clinicians in coming years, the most fundamental questions about genomic imprinting may remain unanswered for a long time.
However, it escapes genomic imprinting in the human.
The NIEHS invites research grant applications from interested investigators to conduct timely, innovative, and mechanistic research on the importance of genomic imprinting in determining susceptibility to environmentally induced diseases through a program of exploratory investigator-initiated R21 grants.
The observations support the role of methylation in genomic imprinting, which by definition requires a mechanism that can switch gears depending on the parent's sex, says Carmen Sapienza of Montreal.
Genomic imprinting, development and disease- is pre-eclampsia caused by a maternally imprinted gene?
This set included genes coding for transcription factors, genes subject to genomic imprinting, genes coding for noncoding RNA, and other genes with restricted or abundant expression in trophoblast cells.
Biological scientists discuss such aspects as fungal models, the epigenetics of ciliates, transcriptional silencing by polycomb group proteins, genomic imprinting in mammals, human disease, and epigenetic determinants of cancer.
The genomic imprinting concept holds that while two genes may contain identical DNA sequences, how a gene behaves may depend on whether the mother or the father provided it.
The biological processes impacted by epigenetics range from tissue/organ regeneration, X-chromosome inactivation, and stem cell differentiation to genomic imprinting and aging.
Topics include DNA methylation and the mammalian genome, methods for the genome-wide and genome-specific analysis of DNA methylation levels and patterns, histone modifications, histone variants and nucleosome occupancy, molecular mechanisms of polycomb silencing, non-coding RNAs in gene regulation, plant epigenetics using a comparative approach, embryonic stem cell epigenetics, the biology of genomic imprinting, X chromosome inactivation, cancer epigenetics, the role of micro DNAs in human cancer, the impact of the environment on epigenetic regulation of gene expression and developmental programming, and trans-generational epigenetic inheritance.
The sins of the fathers and mothers: genomic imprinting in mammalian development.