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A discrete nodular lesion of inflammatory tissue in which granulation is significant.



a focal growth of inflammatory origin in the cells of young connective tissue in the form of a small node.

Granuloma develops in connection with various (most often infectious) processes (tuberculosis, syphilis, leprosy, brucellosis, tularemia, actinomycosis), with collagenic diseases (such as rheumatism), and at the sites of entry of foreign bodies. Certain granulomas have more specific names, such as the tubercle in tuberculosis and the gumma in syphilis.

References in periodicals archive ?
Giant cell reparative granuloma affects patients in a wide age range, with most in their third decade.
Giant cell reparative granuloma is a benign lesion with limited growth potential, usually treated with simple curettage.
3%), 4 of 4 giant cell reparative granulomas (100%), 2 of 4 osteosarcomas (50%), 1 of 15 tenosynovial giant cell tumors (6.
Giant cell reparative granuloma of the cranial vault: Exceptional bone lesion.

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