glioma

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Related to gliomas: meningiomas

glioma

[glī′ō·mə]
(medicine)
A malignant tumor derived from the supporting tissue of the central nervous system.
References in periodicals archive ?
Both features (higher levels in glioblastomas and in supratentorial lateral tumors, which are mainly glioblastomas) may suppose that p53 protein alterations should be a late event in gliomas evolution, as Fults et al[36] and Wu et al[37] have pointed out.
A case-control study of brain gliomas and occupational exposure to chemical carcinogens: the risk to farmers.
Yohay of Johns Hopkins Medical Institutions in Baltimore recently surveyed the amount of EAAT2 in glioma samples from 60 patients.
Temozolomide recently has been approved by the Food and Drug Administration (FDA) for the treatment of recurrent anaplastic gliomas in patients who have failed prior treatment with a nitrosourea.
Although Taxol killed many of the cultured glioma cells, it made the survivors migrate faster than ever, in a dose-dependent fashion.
Researchers at City of Hope previously have identified several proteins as potential prime targets for the development of cancer immunotherapies, such as interleukin 13 receptor alpha 2, a receptor found on the surface of glioma cells, and CD19, a protein that is active in lymphoma and leukemia cells.
High-grade glioma is an aggressive disease that often grows and progresses despite surgery and standard of care chemotherapies.
The 3-D glioma model that we have developed offers a facile process to test diffusion and penetration into a glioma that is covered by a blood vessel-like coating of endothelial cells," said Don Ho, a graduate student in the lab of chemistry professor Shouheng Sun and the lead author of the paper in the journal Theranostics.
Gliomas are fatal, usually within three to five years of diagnosis, even with treatment.
Importantly, IDH1 and IDH2 mutations are not found in nonneoplastic conditions that can histologically mimic gliomas (eg, reactive gliosis, radiation changes, viral infections, infarcts, demyelinating conditions, etc), allowing for improved diagnostic accuracy of suboptimal brain biopsies.
FDA for the treatment of patients with newly-diagnosed high-grade malignant glioma as an adjunct to surgery and radiation, as well as for the treatment of patients with glioblastoma multiforme as an adjunct to surgery.
Sixty international specialists contribute to a text providing the latest information in the diagnosis and management of high-grade gliomas.