gliotoxin


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gliotoxin

[¦glī·ō‚täk·sən]
(microbiology)
C13H14O4N2S2 A heat-labile, bacteriostatic antibiotic produced by species of Trichoderma and Cliocladium and by Aspergillus fumigatus.
References in periodicals archive ?
Mechanism of action of the antifibrogenic compound gliotoxin in rat liver cells," Hepatology, vol.
Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats.
Amphotericine B enhances the synthesis and release of the immunosuppressive agent gliotoxin from the pulmonary pathogen Aspergillus fumigatus.
Richard has applied this test to other mycotoxins, such as gliotoxin and T-2 toxin.
Gliotoxin natural incidence and toxigenicity of Aspergillus fumigatus isolated from maize silage and ready dairy cattle feed.
Although many previous studies have put Gliocladium in a rank of "non-pathogenic fungi", but recent studies have shown the involvement of this organism in the secretion of a kind of fungal toxins called Gliotoxin (38).
These fungi produce a variety of metabolites such as gliotoxin, viridiol, viridian, and gliovirin, which are toxic.
Some of these minor mycotoxins include T-2 toxin, fusaric acid, cyclopiazeaic acid, patulin, gliotoxin, citrinin, and ergot alkaloids.
78) Zinc administration is suggested as a logical therapy for this problem, since it both inhibits the production of gliotoxin in fungal cultures and offers significant protection against formed mycotoxins.
Most of the antagonistic fungi are egg parasitizing but few culture filtrates of these fungi produced the antibiotics, glioviren and gliotoxin (Lumsden et al.