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glucocorticoid

   Also found in: Dictionary/thesaurus, Medical, Acronyms, Wikipedia 0.07 sec.
glucocorticoid [¦glü·kō¦kȯrd·ə‚kȯid]
(biochemistry)
A corticoid that affects glucose metabolism; secreted principally by the adrenal cortex.


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The most common type of CAH is 21-hydroxylase deficiency, within which three severity subtypes are distinguished: Saltwasters (SW), the most severe subtype, in which the enzyme deficiency causes deficiencies of both glucocorticoid (glucose-regulating) and mineralocorticoid (sodium-regulating) hormones; simple virilizers (SV), with moderate deficiencies of glucocorticoids; and the mildest subtype, non-classical (NC), late-onset CAH.
Reduced birth weight and thymus involution, observed upon exposure to organotins, can also be caused by excessive glucocorticoid levels.
 
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