Transaminase

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Related to glutamic-pyruvic transaminase: Serum glutamic oxaloacetic transaminase

transaminase

[¦tranz′am·ə‚nās]
(biochemistry)
One of a group of enzymes that catalyze the transfer of the amino group of an amino acid to a keto acid to form another amino acid. Also known as aminotransferase.

Transaminase

 

(also aminotransferase and aminopherase), an enzyme of the transferase group that catalyzes the transfer of an amino group (—NH2) from an α-amino acid to an α-keto acid. Transaminases are found in most animal and plant tissues and play an important part in nitrogen metabolism. The role of transaminase in the transamination process was discovered by the Soviet biochemists A. E. Braunshtein and M. G. Kritsman in 1937. The coenzyme in transaminase reactions is pyridoxal phosphate, the aldehyde group of which serves as intermediate acceptor of the amino group. The resulting pyridoxamine phosphate transfers the amino group to the ketone group of the acid undergoing amination. The reaction is reversible.

A. A. BOLDYREV

References in periodicals archive ?
2) Total-C = Total cholesterol, GOT = Glutamic-oxaloacetic transaminase, GPT = Glutamic-pyruvic transaminase.
In the presence of anti-SE bacteriophage supplemented in the diet, the responses of glutamic oxalo-acetic transaminase (GOT) and glutamic-pyruvic transaminase (GPT) were not different significantly (p>0.
The dietary effects of CBT[R] on relative weights of liver, spleen and abdominal fat and enzyme of glutamicoxaloacetic transaminase (GOT) and glutamic-pyruvic transaminase (GPT) are shown in Table 4.
2 (1) LDH = Lactate dehydrogenase; BUN = Blood urea nitrogen; GOT = Glutamic-oxaloacetic transaminase; GPT = Glutamic-pyruvic transaminase.
The concentrations of total cholesterol (TC) and the activities of glutamic-oxaloacetic transaminase (GOT) and glutamic-pyruvic transaminase (GPT) in the serum were measured according to the colorimetric method using a cholesterol diagnostic-kit (Cholesterol E kit, Asan Pharmaceutical) and a GOT-GPT assay kit (GOT-GPT assay kit, Asan Pharmaceutical), respectively.
The concentration of total cholesterol and high density lipoprotein-cholesterol (HDL-C), the activity of glutamicoxaloacetic transaminase (GOT) and glutamic-pyruvic transaminase (GPT) were estimated according to the colorimetric method using cholesterol diagnostic kit (Cholesterol E kit, HDL-cholesterol kit, Youngdong Medical Corperation) and GOT-GPT assay kit (BCS GOT GPT assay kit, Bio Clinical System Corporation), following the manufacturer's direction.

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