glutamine synthetase


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Related to glutamine synthetase: glutaminase, glutamate synthase

glutamine synthetase

[′glüd·ə‚mēn ′sin·thə‚tās]
(biochemistry)
An enzyme which catalyzes the formation of glutamine from glutamic acid and ammonia, using adenosine triphosphate as a source of energy.
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3 to 2 >2 times compared with times surroundings Pseudoglands - - [+ or -] + Nodule-in-nodule - - - [+ or -] Portal tract + + + 6 Unpaired arteries and - [+ or -] [+ or -] + capillarized sinusoidsa Stromal invasionb - - - + Reticulin framework + + + [+ or -] Tumor markers Glypican-3 - - [+ or -] (9%) + (69%) Heat shock protein 70 - - [+ or -] (5%) + (78%) Glutamine synthetase - - 6 (13%) + (59%) Positive in at least 2 of - - - + (72%) above 3 markers Abbreviations: -, absent; [+ or -], may be present; +, usually present; (), % of positivity in resected specimen; HGDN, high-grade dysplastic nodule; LGDN, low-grade dysplastic nodule; LRN, large regenerative nodule; WD HCC, well-differentiated hepatocellular carcinoma.
Glutamine synthetase (GS) is a target gene of [beta]-catenin and its overexpression is associated with mutations of [beta]-catenin or with activation of this pathway.
Previous studies have demonstrated that oxidative processes often result in changes of the activities of key enzymes, including glutamine synthetase (GS), creatine kinase (CK) and tyrosine hydroxylase (Hensley et al.
The recent Decision T 356/93 relates to the neutralization of the glutamine synthetase inhibitor in plants.
Fine structural localization of glutamine synthetase in astrocytes of rat brain.
Another possible risk factor is deficiency in a liver enzyme, called glutamine synthetase, which plays a role in ammonia metabolism.
today announced the publication of study results demonstrating glutamine synthetase (GS), an enzyme present in the body, is a highly specific and highly sensitive brain biomarker for Alzheimer's disease (AD).
cell line was the first commercially available glutamine synthetase (GS) knockout CHO line on the market.

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