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It has been postulated that the protective property of a biofilm glycocalyx is evident in the difficulty that patients with cystic fibrosis have in controlling pseudomonal pulmonary infections.
A healthy glycocalyx is imperative in maintaining normal vascular and micro-vascular functions, especially as relates to the body's ability to resist circulating blood components from inadvertently sticking to the arterial wall.
Commensal organisms may synthesize glycosidase, leading to damage of glycocalyx or disaccharidases.
8) The sticky glycocalyx helps to prevent pathogens from adhering to and entering the corneal epithelium and also converts the epithelium from a hydrophobic to a wettable surface.
The authors concluded that in the sequence of exine development four main stages can be recognized, each with a different mechanism for wall construction: (1) formation of glycocalyx by self-assembly of micelles, (2) insertion of sporopollenin receptors under control of genome, (3) accumulation of receptor-dependant sporopollenin under control of sporopollenin receptors and (4) accumulation of receptor-independent sporopollenin by self-assembly.
2007, "The role of endothelial glycocalyx components in mechanotransduction of fluid shear stress", Biochem Biophys Res Commun 355: 228-233.
One of the challenging aspects of pseudomonal endocarditis treatment is the requirement of higher concentration of antimicrobial agents, as penetration of the antimicrobial agent is decreased to the bacterial cell because of polyanionic glycocalyx biofilm formation of P.
Bacteria gain access to the lower respiratory tract via aspiration through the endotracheal tube (where they may establish colonies impervious to the effects of antibiotics in the glycocalyx biofilm that coats the lumen of the artificial airway devices), migration around it (particularly if cuff inflation pressure is not maintained), or, in rare instances, hematogenous spread from blood stream infections.
The method is based on the observation that mature spermatozoa are more electronegative due to the negatively charged glycocalyx rich in sialic acid residues.
Concanavalin A-induced discharge of glycocalyx of raphidophycean flagellates, Chattonella marina and Heterosigma akashiwo.
Bacteria readily bind to the materials used in joint arthroplasties, and, once attached to the implant, some bacteria produce a surface glycocalyx that protects them from the host inflammatory response.
Protein glycans are interconnected with glycocalyx of cellular membranes.