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glycolytic pathway |
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glycolysisor glycolytic pathway or Embden-Meyerhof-Parnas pathwaySequence of 10 chemical reactions taking place in most cells that breaks down glucose, releasing energy that is then captured and stored in ATP. One molecule of glucose (plus coenzymes and inorganic phosphate) makes two molecules of pyruvate (or pyruvic acid) and two molecules of ATP. The pyruvate enters into the tricarboxylic acid cycle if enough oxygen is present or is fermented into lactic acid or ethanol if not. Thus, glycolysis produces both ATP for cellular energy requirements and building blocks for synthesis of other cellular products. See also Gustav Georg Embden, Otto Meyerhof. glycolytic pathway [¦glī·kə¦lid·ik ′path‚wā] (biochemistry) The principal series of phosphorylative reactions involved in pyruvic acid production in phosphorylative fermentations. Also known as Embden-Meyerhof pathway; hexose diphosphate pathway. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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No references found | 5), (6) Since the TCA cycle has been turned off in cancer cells, the only ATP-generating pathway remaining in operation is the glycolytic pathway from sugar to pyruvate/lactate, producing a much smaller amount of ATP compared with that of the TCA cycle. The total capacity of the glycolytic pathway is limited by the progressive increase of acidity within the muscles, caused by the accumulation of hydrogen ions (Verbitsky et al. At the final stage of maturation haemoglobin synthesis ceases and the immature cells become mature reticulocytes and mature into erythrocytes, which have no mitochondria, RNA and ribosomes, while retaining the ability to utilize glucose in glycolytic pathways. |
glycolytic pathway |
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