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goitre |
Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson | 0.04 sec. |
goitreEnlargement of the thyroid gland, causing a prominent swelling in the front of the neck. The thyroid normally weighs 0.5 to 0.9 oz (15 to 25 g); however, goitrous thyroid glands can grow to more than 2 lbs (1,000 g). A large goitre may interfere with breathing and swallowing and cause a choking feeling. Endemic goitre, the most common, is due to iodine deficiency, which causes a reduction in thyroid hormone synthesis (hypothyroidism). As a result, there is a compensatory increase in secretion of the anterior pituitary hormone thyrotropin. Thyrotropin not only stimulates thyroid hormone production but also causes an increase in size and number of cells in the thyroid. Advanced cases are treated with thyroid hormone or with surgical removal of the thyroid if it obstructs breathing. There are numerous other causes of goitre, including defects in thyroid hormone synthesis and inflammation of the thyroid. An enlarged thyroid may have normally functioning tissue or may produce too much hormone (hyperthyroidism). See also Graves disease. |
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| But that suitable discourse might not fail, Fate sent them, overtaking and overtaken upon the road, the courteous Dacca physician, who paid for his food in ointments good for goitre and counsels that restore peace between men and women. Here and there we passed Cszeks and slovaks, all in picturesque attire, but I noticed that goitre was painfully prevalent. The child carried in a sling by the laden peasant woman toiling home, was quieted with picked-up grapes; the idiot sunning his big goitre under the leaves of the wooden chalet by the way to the Waterfall, sat Munching grapes; the breath of the cows and goats was redolent of leaves and stalks of grapes; the company in every little cabaret were eating, drinking, talking grapes. |
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