gonadal dysgenesis


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Related to gonadal dysgenesis: gonadal agenesis, Swyer syndrome, XY gonadal dysgenesis

gonadal dysgenesis

[gō′nad·əl dis′jen·ə·səs]
(medicine)
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References in periodicals archive ?
The gonads of XY pure gonadal dysgenesis have a high risk of gonadoblastoma and germ cell tumour, particularly dysgerminoma.
Pregnancy can be achieved or fertility can be optimised by using donor oocytes, and successful pregnancies in patients with pure gonadal dysgenesis have been described.
The putative gene that predisposes patients with disorders of sex development and gonadal dysgenesis to develop germ cell tumors is the testis-specific protein Y-encoded (TSPY) gene located on the Y chromosome.
103) Clinical presentation includes short stature, sexual infantilism, gonadal dysgenesis with streak gonads, and primary amenorrhea.
A clinical and cytogenetic study of fifteen patients with 45,X/46XY gonadal dysgenesis.
Alopecia universalis congenita, XY gonadal dysgenesis and laryngomalacia: A novel malformation syndrome.
In fact, some authors consider DMP a variant of mixed gonadal dysgenesis,[4,8-9] which is defined as the coexistence of a streak gonad and a dysgenetic testis in a patient with a 45,X/46,XY karyotype.
Even though there are technical pitfalls in evaluating the mean tubular diameter, our data indicate the need for this evaluation in all testicular biopsies when there is clinical suspicion of gonadal dysgenesis, independent of the gonadal location.
2002) showed that atrazine exposure (21 ppb) for as little as 48 hr resulted in severe gonadal dysgenesis in African clawed frogs (Xenopus laevis).