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gramicidin

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.03 sec.
gramicidin (grăm'ĭsīd`ən), antibiotic antibiotic, any of a variety of substances, usually obtained from microorganisms, that inhibit the growth of or destroy certain other microorganisms.

Types of Antibiotics


..... Click the link for more information.  obtained from the bacterial species Bacillus brevis, which is found in soil. Gramicidin is particularly effective against gram-positive bacteria (see Gram's stain Gram's stain, laboratory staining technique that distinguishes between two groups of bacteria by the identification of differences in the structure of their cell walls.
..... Click the link for more information. ). Because the drug is highly toxic, it cannot be administered internally and so is used only on the skin as a lotion or ointment. It is used primarily in the treatment of infected surface wounds, and in eye, nose, and throat infections. In 1939 the American microbiologist René Dubos isolated the substance tyrothricin and later showed that it was composed of two substances, gramicidin and tyrocidine. These were the first antibiotics to be manufactured commercially.
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Neomycin and Polymyxin B Sulfates and Gramicidin Ophthalmic Solution
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They discovered that the new nanotubes conducted ions as effectively as the eight-ringed ones and more efficiently than gramicidin A, a natural peptide channel with antibiotic properties.
Peptide nanotube acts as tunnel for ions by Wu, Corinna / Science News
The researchers compared three such agents: nonoxynol-9, gramicidin and PRO 2000.
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