Granulations


Also found in: Dictionary, Thesaurus, Medical.

Granulations

 

in medicine, the moist, bright red tissue with granular surface that develops during the healing of wounds of inflammatory foci.

Granulations are rich in blood vessels and young connective-tissue cells, which rapidly proliferate and replace the destroyed section of tissue. When there is excessive formation of granulations, such as in the area surrounding a fistula (so-called proud flesh), healing is impaired. Granulations of this sort are removed surgically.

References in periodicals archive ?
The roller compaction process is well established as a dry granulation continuous process as long as the blended composition of powders are supplied and post compaction process is aligned to produce subsequent blending and compression/encapsulation operation.
The otorrhoea, unlike seen in suppurative otitis media, is not due to a built up of tension but rather due to the granulations formed over areas of tympanic membrane as a result of the tubercular process.
After granulation, the material is discharged through the milling equipment and can be either vacuumed into the bowl or into the drying equipment.
With respect to granulations, Dawes reminded his readers that: "Their existence was well known to Sir W.
A significant advancement in HuberEoACAOs particle engineering capacity was made in 2007 with the addition of fluid bed granulation and trituration.
For realizing the study of the pieces porosity variations dependent on the powder granulation have been used powders: 56 [micro]m, 63 [micro]m, 100 [micro]m, and >160 [micro]m.
One key reason is that Starch 1500 performs multiple functions within a wet granulation formulation: as a binder, disintegrant, filler and lubricant, eliminating the need for a multitude of costly excipients and additional processing steps.
These granulations are primarily located in the vicinity of dural venous sinuses and most are close to the sagittal sinus.
A HORN manufacturing division, Nutri Granulations works to provide engineered granulation solutions through their state-of-the-art cGMP drug manufacturing facility.
For example, if the API can be converted from one morphic form to another then it will need to be monitored at key steps including milling, granulation and compression.
Custom granulations and blends; formulation and product development