Because of its rarity, screening for granulocytic
sarcoma among patients with acute myeloid leukemia is not routinely done (Meltzer & Jubinsky, 2005).
These findings didn't surprise Dumler, one of the discoverers of granulocytic
The gram-negative bacterium Anaplasma phagocytophilum is the causative agent of human granulocytic
anaplasmosis (HGA) in the United States (1).
There was left-shifted granulocytic
maturation with increased numbers of blasts (4%-6%) and promyelocytes.
s case report entitled, Cerebellar granulocytic
sarcoma: A case report (2012; 19: 177-180), (1) provides an opportunity for me to remind physicians that short-course megadose methylprednisolone (MDMP: 30 mg/kg for 3 d, then 20 mg/kg for 4 d each dose administered over the course of 10-15 min intravenously or orally; calculated dose of powder put into a spoon and then covered with honey and administered before 0600), has been effectively used for the treatment of granulocytic
sarcoma (GS) (2), (3), (4), (5).
The bone marrow also exhibited multifocal necrosis and fibrin exudation as well as marked erythroid and lesser granulocytic
hyperplasia with intralesional protozoan cysts.
Acute promyelocytic leukemia arises out of a defect in normal granulocytic
cell maturation and apoptosis.
Disease-specific diagnosis of coinfecting tickborne zoonoses: babesiosis, human granulocytic
ehrlichiosis, and Lyme disease.
Acute myeloid leukemia with recurrent t(8;21) generally shows granulocytic
differentiation with maturation, and no specific immunophenotypic or morphologic evidence of monocytic, erythroid, or megakaryoblastic differentiation.
Lesions included adnexal neoplasm, ameloblastic fibro-odontoma, basal cell carcinoma, benign fibrous histiocytoma, blue nevus, chondrosarcoma, compound nevus, epithelioma adenoides cysticum, esthesioneuroblastoma, Ewing sarcoma, fibrosarcoma, giant cell granuloma, granulocytic
sarcoma, hemangioma, hemangiopericytoma, Langerhans cell histiocytosis, lymphangioma, lymphoma, melanoma, neuroblastoma, neurofibroma, ossifying osteofibroma, osteochondroma, osteosarcoma, port wine stain, rhabdomyosarcoma, Spitz nevus, and xanthogranuloma.
According to provincial health authorities, the 18 victims were among 557 reported cases of suspected human granulocytic
anaplasmosis (HGA) since May 2007.
Since this red-colored crystal was discovered as a compound with antileukemic properties by Chinese researchers in the Traditional Chinese Medicine Danggui Longhui Wan, which was effective against chronic granulocytic
leukemia (Bradbury, 2005).