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Related to granulomata: granulomatous inflammation, Granulomatous disease, Giant cells


A discrete nodular lesion of inflammatory tissue in which granulation is significant.



a focal growth of inflammatory origin in the cells of young connective tissue in the form of a small node.

Granuloma develops in connection with various (most often infectious) processes (tuberculosis, syphilis, leprosy, brucellosis, tularemia, actinomycosis), with collagenic diseases (such as rheumatism), and at the sites of entry of foreign bodies. Certain granulomas have more specific names, such as the tubercle in tuberculosis and the gumma in syphilis.

References in periodicals archive ?
9, 11) Such solitary lytic lesions involving the subarticular region of large joints may mimic bone neoplasms and may be called "tuberculous pseudotumors" or "tumor-like tuberculous granulomata.
Granulomata consist of focal collections of macrophages, a few multinucleated giant cells, and scanty surrounding lymphocytes.
Detection of mummified remnants of individual necrotic epithelioid cells in the centers of the tumor nodules, as opposed to the suppurative, fibrinoid, or caseous necrosis of necrotizing granulomata, or the accumulated stromal mucin of granuloma annulare should also alert one to the possibility of epithelioid sarcoma.

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