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growth cone

   Also found in: Dictionary/thesaurus, Medical, Legal, Financial, Wikipedia 0.01 sec.
growth cone [′grōth ‚kōn]
(neuroscience)
A specialized structure at the end of a growing nerve fiber that guides the fiber to its destination during the development of the nervous system by means of interaction with signaling molecules in its surroundings and its own motile mechanism.


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Other topics include quantum dots as cellular probes, microfluidic and microfabricated devices for blood cell separation, growth cone and axonal pathfinding strategies, the mechanics of healing myocardial infarcts, and functional electrical stimulation for neuromuscular applications.
When EphA4 binds to an ephrin ligand it initiates a cascade of intracellular signalling events that will ultimately cause the growth cone to steer away from the area.
The investigators report that in lab dishes, the drugs affect nerve cell extensions known as growth cones by, for example, increasing their size.
 
 
 
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