antagonist

(redirected from growth hormone receptor antagonist)
Also found in: Dictionary, Thesaurus, Medical, Legal, Wikipedia.

antagonist

1. any muscle that opposes the action of another
2. a drug that counteracts the effects of another drug

antagonist

[an′tag·ə‚nist]
(biochemistry)
A molecule that bears sufficient structural similarity to a second molecule to compete with that molecule for binding sites on a third molecule.
(pharmacology)
A drug or other chemical substance capable of reducing the physiological activity of another chemical substance; refers especially to a drug that opposes the action of a drug or other chemical substance on the nervous system by combining with and blocking the nerve receptor.
(physiology)
A muscle that contracts with, and limits the action of, another muscle, called an agonist, with which it is paired.
References in periodicals archive ?
Not only is there a clear medical need for a growth hormone receptor antagonist with improved half-life, but this program initiates the application of DiAthegen's technology to an array of protein therapeutics in the growth hormone and diabetes area that will benefit from extended pharmacokinetics.
That market is currently dominated by once-a-month Sandostatin LAR(R) Depot (octreotide acetate for injectable suspension) from Novartis (NYSE: NVS) and includes daily injections of Somavert (pegvisomant for injection), a growth hormone receptor antagonist, from Pfizer (NYSE: PFE).

Full browser ?