, bio-conjugation, nucleic acid synthesis
KP-1212 can replace cytidine when the viral enzyme reverse transcriptase is building a new copy of HIV, and pair normally with guanosine
For 2-deoxyinosine, adenosine, 2-deoxyadenosine, guanosine
, 2-deoxyguanosine, succinyladenosine, orotic acid, thymine, dihydrouracil, dihydrothymine, uridine, 2-deoxyuridine, and 5-hydroxymethyluracil, sample concentrations were below the lower limits of quantification, as were the concentrations of inosine and N-carbamyl-[beta]-aminoisobutyric acid for children older than 1 year and N-carbamyl-[beta]-alanine for children older than 4 years of age.
Sildenafil dilates penile arteries through cyclic guanosine
monophosphate (cGMP), and penile erection is achieved by increasing penile blood flow.
5'-triphosphate (GTP) plays a pivotal role in many
Mammalian cells, in contrast, convert fucose from their surroundings into a form called guanosine
diphosphate-fucose (GDP-fucose), which they attach to their surface proteins.
Effect of guanosine
nucleotides and adenosine deaminase on CGS 21680 activation effect
They found that Viagra, by elevating levels of a compound in cells called cyclic guanosine
monophosphate, or cGMP, actually encourages platelets to aggregate, thus amending 20 years of scientific claims that the compound acts to prevent platelet aggregation.
b) GC= (Guanosine
(G) + Cytidine (C))/ (Adenosine (A)+ Thymidine (T)+ Guanosine
(G) + Cytidine (C)) x 100 Table 2.
The same effect was seen with a sugar-like molecule called cyclodextrin, guanosine
monophosphate, DNA, and table salt.
16] This in turn stimulates activation of guanine nucleotide exchange factors, which promote the formation of the active guanosine
triphosphate (GTP)-bound form of Ras.
Unblocking may also occur with guanosine
analogs, such as abacavir (Ziagen), perhaps explaining the diminished response to abacavir in patients with pre-existing zidovudine resistance.