Guanosine

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guanosine

[′gwän·ə‚sēn]
(biochemistry)
C10H13O5N5 Guanine riboside, a nucleoside composed of guanine and ribose. Also known as vernine.

Guanosine

 

the nucleoside consisting of the carbohydrate ribose and the nitrogen base guanine. Colorless crystals. Molecular weight, 283.26 and melting point. 235° C. Free guanosine is an intermediate product of metabolism. It is a component of nucleic acids and biologically active guanyl nucleotides, GMP, GDP. and GTP. GTP (guanosine triphosphate), an energy-rich phosphorus compound, is a coenzyme of some reactions, such as the amination of inosinic acid and the transference of amino acids to ribosomes during the biosynthesis of protein.

References in periodicals archive ?
Diffusible nitric oxide gas penetrates vascular smooth muscle and activates soluble guanylyl cyclase which catalyzes which catalyzes guanosine triphosphate to form cyclic guanosine monophosphate (Da Silva Rde et al.
Another possible mechanism involves l-arginine-nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signaling pathway.
To evaluate the effect of increased concentrations of cytosolic cyclic guanosine monophosphate (cGMP) on pigment aggregation, we employed dibutyryl 3' :5'-cyclic guanosine monophosphate (db-cGMP, 10 [micro]mol [l.
NO formation and cyclic guanosine monophosphate production within platelets was increased during the luteal phase of the cycle compared with the follicular phase in patients with menstrual migraine, suggesting that enhanced NO production could be involved in menstrual migraine pathogenesis if platelet abnormalities reflect events within the central nervous system or vascular endothelium.
The inability to digest microorganisms is related to low levels of intracellular cyclic guanosine monophosphate and diminished release of [beta]-glucuronidase.
Erections occur when a stimulus triggers the release of nitric oxide, which activates cyclic guanosine monophosphate (cyclic GMP), an enzyme that causes the smooth muscle of the penis to relax and blood flow to increase.
This interaction involves the NO/cyclic guanosine monophosphate (NO/cGMP) pathway.
They found that Viagra, by elevating levels of a compound in cells called cyclic guanosine monophosphate, or cGMP, actually encourages platelets to aggregate, thus amending 20 years of scientific claims that the compound acts to prevent platelet aggregation.
Known as cyclic guanosine monophosphate, or cGMP, the chemical may also play a role in the normal control of any mammal's digestive system.
Also, the substances nitric oxide (NO) and cyclic guanosine monophosphate (cGMP) are incorrectly described as having separate effects on smooth muscle cells (pages 26 and 104, table 11.
Nitric oxide then activates the enzyme guanylate cyclase which causes increased levels of cyclic guanosine monophosphate (cGMP), which produces smooth muscle relaxation in the corpus cavernosum and allows for an inflow of blood resulting in an erection.