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Guanosine
(redirected from guanosine monophosphate)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.03 sec.
guanosine [′gwän·ə‚sēn]
(biochemistry)
C10H13O5N5Guanine riboside, a nucleoside composed of guanine and ribose. Also known as vernine.

Guanosine 

the nucleoside consisting of the carbohydrate ribose and the nitrogen base guanine. Colorless crystals. Molecular weight, 283.26 and melting point. 235° C. Free guanosine is an intermediate product of metabolism. It is a component of nucleic acids and biologically active guanyl nucleotides, GMP, GDP. and GTP. GTP (guanosine triphosphate), an energy-rich phosphorus compound, is a coenzyme of some reactions, such as the amination of inosinic acid and the transference of amino acids to ribosomes during the biosynthesis of protein.



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Along with increasing blood flow in arteries, Viagra interferes with phosphodiesterases (PDEs), enzymes that break down the messenger molecule called cyclic guanosine monophosphate (cGMP), which would otherwise "put the brakes on" heart muscle cell growth.
They found that Viagra, by elevating levels of a compound in cells called cyclic guanosine monophosphate, or cGMP, actually encourages platelets to aggregate, thus amending 20 years of scientific claims that the compound acts to prevent platelet aggregation.
Known as cyclic guanosine monophosphate, or cGMP, the chemical may also play a role in the normal control of any mammal's digestive system.
 
 
 
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