Christmas disease

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Related to haemophilia B: haemophilia A, Hæmophilia A, Haemophilia C

Christmas disease

[′kris·məs di‚zēz]
(medicine)
A hereditary, sex-linked, hemophilia-like disease involving failure of the clotting mechanism due to a deficiency of Christmas factor. Also known as Factor IX deficiency.
References in periodicals archive ?
Distribution of Haemophilia according to Severity and Types Type Moderate Severe Total Haemophilia A 3 27 30(75%) Haemophilia B 2 8 10(25%) Total 5 (12.
Alprolix has been developed for haemophilia B by fusing factor IX to the Fc portion of immunoglobulin G subclass 1, or IgG1 (a protein commonly found in the body).
Haemophilia B is said to occur in about one in 25,000 male births annually, but more rarely in females.
The company added that Alprolix is currently approved for the treatment of haemophilia B in the EU, Iceland, Liechtenstein and Norway, as well as the US, Canada, Japan, Australia, New Zealand and other countries.
Haemophilia B is also referred to as Christmas disease.
6 Correct diagnosis of haemophilia B depends on availability of screening coagulation tests (APTT, PT) correction studies and finally one stage APTT based assay of the deficiency factors to assess the severity of the disease.
This might help to facilitate new diagnostic and therapeutic strategies for haemophilia B patients.
In a total of 349 patients 45 were diagnosed as Haemophilia B during the period of 2005 to 2008.
Percentage of Patients with Haemophilia A and Haemophilia B Factor VIII deficiency 80% Factor IX deficiency 20% Note: Table made from pie graph.