haplotype


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haplotype

[′hap·lə‚tīp]
(genetics)
A set of alleles of closely linked loci on a chromosome that tend to be inherited together; commonly used in reference to the linked genes of the major histocompatibility complex.
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Here, we developed an in vitro model to explore the modulation of PTGS2 expression by haplotypes combining SNPs from both the PR and the 3'-UTR.
Our technology, with its unique ability to resolve and haplotype genomic information, is well suited for developing NIPT applications.
However, this haplotype information does not represent the relationship among the geographical origins of duck with the certain name of duck species.
Of the 58 samples from which Red Fox mtDNA was successfully extracted, 46 (79%) were of the cytochrome b/D-loop haplotype combination A-19 (Table 1), the most common haplotype in native populations from the Rocky Mountains, Sierra Nevada, and the Cascade Range of Oregon (Aubry and others 2009).
17 Kawasaki originated from a single haplotype from which rapid genetic diversification into multiple sublineages occurred during global spread after the initial emergence in China in late 2014.
sup][50] showed that the haplotype HLA-A*3303-Cw*1403-B*4403-DRB1*1302-DQB1*0604-DPB1*0401 reduced the risk of Grade 2 to 4 aGVHD, whereas HLA-A*2402-Cw*0702-B*0702-DRB1*0101-DQB1*0501-DPB1*0402 tended to increase the risk in allo-HSCT.
The genetic variation for each group was evaluated using empirical descriptive values such as haplotype diversity (h), nucleotide diversity ([pi]) (Nei, 1987) and segregated sites (S) (Nei & Kumar, 2000).
2), the frequencies of the dominant haplotype in the female, the male, and the megalopa were, respectively, 72.
All nucleotide substitutions were silent (no change in amino acid sequence) except one (site 623 in haplotype h3; Table 3).
Recently, a direct haplotype phasing approach using microfluidics-based linked-read sequencing technology became available (21).
This haplotype has been previously detected in many black sheep breed worldwide (Table 5).
The remaining part of the target region was found to reveal 24 polymorphic sites in these 15 sequences which were assembled into 4 haplotypes (Table 1).