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hapten

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
hapten
(immunology)
An incomplete antigen that cannot induce antibody formation by itself but can do so by coupling with a larger carrier molecule.


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Hapten hipotezine gore ilac proteinlere kovalan baglarla baglandiktan sonra immun sistemi uyarabilir.
1- Haptenler 2- Epidermal hucreler: keratinositler ve Langerhans hucreleri 3- CD4+T hucreleri 4- Reaktif hucreler: monositler, makrofajlar ve notrofiller Alerjenler dusuk molekul agirlikli (500-1000 dalton) maddeler olup hapten yapisindadirlar (9).
Epitopa ozgul baskilanma: Tetanoz ve difteri toksoidi gibi tasiyicilara karsi onceden gelismis antikor varliginda, bu tasiyicilar ile verilen hapten polisakkarid epitoplara karsi bagisiklik yanitinda azalma gorulur(6).
 
 
 
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