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helper virus

   Also found in: Dictionary/thesaurus, Medical, Legal, Wikipedia 0.03 sec.
helper virus [′hel·pər ‚vī·rəs]
(virology)
A virus that, by its infection of a cell, enables a defective virus to multiply by supplying one or more functions that the defective virus lacks.


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Production of AAV vectors requires the introduction of several elements into a cell, including the AAV vector and gene of interest, AAV rep and cap genes and genes provided from a helper virus.
In general, AAV2 requires association with a helper virus in order to replicate.
The helper virus carries the instructions for fabricating new virus outer coats, but cannot make copies of the virus' own genes.
 
 
 
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