helper virus


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helper virus

[′hel·pər ‚vī·rəs]
(virology)
A virus that, by its infection of a cell, enables a defective virus to multiply by supplying one or more functions that the defective virus lacks.
References in periodicals archive ?
The use of multiple separation techniques removes helper virus from the vector preparation and a robust heat inactivation step disables any remaining helper virus without affecting the activity of AAV vectors.
This helper virus can be transferred into any suitable host cell making it a packaging cell.
Production of AAV vectors involves the introduction of several elements into a permissive cell; the AAV vector and gene of interest, AAV rep and cap genes and a helper virus.