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hemoglobin E

   Also found in: Medical 0.04 sec.
hemoglobin E [′hē·mə‚glō·bən ′ē]
(pathology)
An abnormal hemoglobin found in people of Southeast Asia, migrating slightly faster than hemoglobin C; in the homozygous form it causes a mild hemolytic anemia with normochromic target cells.


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Hemoglobin E, the second most common hemoglobinopathy worldwide, may be difficult to identify using our HPLC system because this hemoglobin coelutes with hemoglobin A^sub 2^.
The hemoglobin A^sub 2^ level cannot be assessed from the high-performance liquid chromatography data, because hemoglobin E has the same retention time as hemoglobin A^sub 2^ and overlaps the A^sub 2^ pick (Figure 3, the shaded area).
 
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