hemoglobin (hē`məglō'bĭn), respiratory protein found in the red blood blood, fluid pumped by the heart that circulates throughout the body via the arteries, veins, and capillaries (see circulatory system ; heart ). An adult male of average size normally has about 6 quarts (5.6 liters) of blood.
..... Click the link for more information. cells (erythrocytes) of all vertebrates and some invertebrates. A hemoglobin molecule is composed of a protein group, known as globin, and four heme groups, each associated with an iron atom.

In the lungs, each iron atom combines reversibly with a molecule of oxygen. Each hemoglobin molecule also has attached a single cysteine amino acid, which attracts nitric oxide from the lungs. The enriched hemoglobin circulates and is carried through the body to the tissues, where the nitric oxide dilates the small capillaries, allowing hemoglobin to deliver its oxygen to the tissues. Then the oxygen- and nitric oxide–free hemoglobin molecule picks up carbon dioxide and free nitric oxide and transports both back to the lungs, where they are exhaled as waste.

Hemoglobin is produced in bone marrow Bone marrow transplantation is a technique that infuses healthy bone marrow into a patient whose bone marrow is defective. The transplant can be autologous, consisting of bone marrow removed from the patient, treated, and then reinserted, or it can be allogeneic, consisting of
..... Click the link for more information. by erythrocytes and is circulated with them until their destruction. It is then broken down in the spleen, and some of its components, such as iron, are recycled to the bone marrow. Other components, such as the heme groups, are broken down into bilirubin, transported to the liver, and secreted with the bile bile, bitter alkaline fluid of a yellow, brown, or green color, secreted, in man, by the liver. Bile, or gall, is composed of water, bile acids and their salts, bile pigments, cholesterol, fatty acids, and inorganic salts.
..... Click the link for more information. into the intestine for eventual elimination from the body.

Hemoglobin deficiency may be a result of structural abnormality in the hemoglobin molecules themselves. In sickle cell disease sickle cell disease or sickle cell anemia, inherited disorder of the blood in which the oxygen-carrying hemoglobin pigment in erythrocytes (red blood cells) is abnormal.
..... Click the link for more information. , this structural abnormality creates malformed red blood cells which clog blood vessels, severely restricting the supply of blood flowing to body tissues.

hemoglobin

Protein in the blood of many animals (in vertebrates it is in red blood cells) that transports oxygen from the lungs to the tissues. It is bright red when combined with oxygen and purple-blue in the deoxygenated state. Each molecule is made up of a globin (a type of protein) and four heme groups. Heme, a complex heterocyclic compound, is an organic molecule derived from porphyrin with an iron atom at the centre. Variant hemoglobins (see sickle-cell anemia; hemoglobinopathy) can be used to trace past human migrations and to study genetic relationships among populations.

hemoglobin (redirected from hemoglobin-oxygen dissociation curve)

hemoglobin

hemoglobin
(redirected from hemoglobin-oxygen dissociation curve)