hemoglobinopathy


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Related to hemoglobinopathy: Hemoglobin electrophoresis

hemoglobinopathy

[‚hē·mə‚glō·bə′näp·ə·thē]
(medicine)
Any blood dyscrasia resulting from the genetically determined alteration of the chemical nature of hemoglobin.
References in periodicals archive ?
The study sample comprised the couples attending to the Mother and Child Health Care Center in Hatay for premarital hemoglobinopathy screening from 2004 to 2009.
An alternative and less expensive algorithm is to screen new patients for hemoglobinopathy by utilizing HPLC HbA1c.
A new hereditary hemoglobinopathy (the Lepore trait) and its interaction with thalassemia trait.
Reprints: John Lafferty, ART, Hemoglobinopathy Laboratory, St Joseph's Hospital, 50 Charlton Ave E, Hamilton, Ontario, Canada L8N 4A6.
We, and our collaborators at Biogen, will also present data from our hemoglobinopathy programs in beta-thalassemia and sickle cell disease, which use an efficient ZFN-mediated knockout approach in hematopoietic stem cells to elevate functional globin to provide a potentially life-long therapeutic effect.
High-resolution HbA(1c) separation and hemoglobinopathy detection with capillary electrophoresis.
In conclusion, educational programs are very important for prevention thalassemia and hemoglobinopathy.
List two compound heterozygotes that mimic other hemoglobinopathy and/or thalassemia conditions.
Although the pathogenesis of this colonic pseudo-obstruction is uncertain, the pattern of the illness indicates a strong etiologic association with the sickling hemoglobinopathy rather than a coincidental occurrence.
Several academic groups investigating ZFP therapeutic approaches to monogenic diseases, including the immune disorder X-chronic granulomatous disease (X-CGD)(Abst# 280) and the hemoglobinopathy, alpha-thalassemia, (Abst# 568) described the application of Sangamo's ZFN technology to insert therapeutic genes into "safe harbor" sites.