hemosiderin


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Related to hemosiderin: hemosiderosis

hemosiderin

[‚hē·mō′sid·ə·rən]
(biochemistry)
An iron-containing glycoprotein found in most tissues and especially in liver.
References in periodicals archive ?
Remote hemorrhage can be replaced by hemosiderin, and the areas may be infiltrated by hemosiderin-laden histiocytes (D, arrowheads) (hematoxylin-eosin, original magnifications X200 [A] and X400 [B through D]).
Histopathologically AS shows degenerative features like hemorrhage, hemosiderin pigmentation, cellular atypia, areas of myxoid degeneration.
Histological examination of the excision piece described characteristics compatible with PVNS, with areas of extensive necrosis and the presence of hemosiderin deposits.
Consequently, these cells have phagocytosed the hemosiderin as a result of erythrocyte lysis, as described by Ramos et al (24) in visceral granuloma naturally diagnosed in cultured Sparus aurata.
These findings were demonstrated on a background of multifocal cerebral hemorrhage, as evidenced by hemosiderin laden macrophages seen in figure 7 (arrow), as well as neurofibrillary tangles and neuritic plaques characteristic of Alzhemer's disease.
Lymphoplasmacytic infiltrate, xanthoma cells, hemosiderin, and calcification are seen (H&E stain, x200).
Interestingly, the hemosiderin in haemophilic arthropathy is derived from the phagocytosis of red blood cells after the formation of joint hematoma via intra-articular bleeding [10].
We could not identify the changes in epidermis, due to the extended skin ulceration, but the tumor proliferation was almost similar to the above description, the small vascular channels being associated with abundant hemorrhage and hemosiderin pigment.
Hemosiderin, lipofuscin, minocycline itself or its quinone by-product, have also been suggested since the presence of minocycline crystals has been demonstrated in up to 32% of localised pigmentation.
CMB is diagnosed using MRI scans to detect deposits of the iron-storing blood protein hemosiderin in brain tissue near cerebral blood vessels.