hemosiderin


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Related to hemosiderin: hemosiderosis

hemosiderin

[‚hē·mō′sid·ə·rən]
(biochemistry)
An iron-containing glycoprotein found in most tissues and especially in liver.
References in periodicals archive ?
The serum ferritin level was extremely high in Case 1 (Table 1) and the liver biopsy also exhibited hemosiderin accumulation.
1975) based on the hemosiderin content of alveolar macrophages stained with Prussian blue.
Hemosiderin deposition in portal endothelial cells is a histological marker predicting poor response to interferon-a therapy in chronic hepatitis C.
In the post-surgical histological examination of this structure, extrasynovial osteochondroma was reported in the IFP since the well-differentiated osteocartilaginous tissue was surrounded by fibroadipose tissue and contained hemosiderin pigments.
Evidence of inflammation and maternal or fetal vascular anomalies were dominant, such as chronic intervillositis, hypercoiled cord with umbilical and chorionic thrombi, and chorionic hemosiderin deposition suggestive of previous intrauterine bleeding.
The cyst contents maybe a mixture of benign colloid debris of cholesterin crystals, hemosiderin, mucus, desquamated epithelial cells, leukocytes, or cholesterol pigment.
As a consequence of repeated episodes of hemorrhage, which are common within schwannoma tissue, vascular thrombosis and hemosiderin deposits can be found.
A liver biopsy performed at 7 weeks of age showed histological features consistent with iron overload with hepatocytes with hemosiderin pigment, fibrosis of the portal tracts, and canalicular cholestasis (Figure 2).
Superficial siderosis involves hemosiderin deposition on the surface of the brain, cord and cranial nerves.
Histologically, a thin, several cell thick lining with deeper layers of fibrous tissue, giant cells containing hemosiderin, and cholesterol clefts are present.
The liver tissue was trimmed, processed conventionally, embedded in paraffin, sectioned at about 4 [micro]m, and stained with hematoxylin (aluminum-hematein) and eosin (H&E) and periodic acid-Schiff for routine diagnostics; Van Gieson and Masson Trichrome to detect fibrous tissue (collagen); Best's carmine to demonstrate glycogen storage; Sudan III to detect lipid (frozen tissue); and Perls' Prussian blue reaction and Schmorl technique for detecting hemosiderin and lipofuscin pigments, respectively (Bancroft and Stevens 1996; Lyon et al.
Two-thirds of the body's iron is present in hemoglobin, myoglobin, and iron-containing enzymes, with the remainder occurring in the storage forms, ferritin and hemosiderin.