heparin


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Related to heparin: Heparin induced thrombocytopenia

heparin

(hĕp`ərĭn), anticoagulantanticoagulant
, any of several substances that inhibit blood clot formation (see blood clotting). Some anticoagulants, such as the coumarin derivatives bishydroxycoumarin (Dicumarol) and warfarin (Coumadin) inhibit synthesis of prothrombin, a clot-forming substance, and other
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 produced by cells in many animals. A polysaccharide, heparin is found in the human body and occurs in greatest concentration in the tissues surrounding the capillaries of the lungs and the liver. The substance, extracted from animal tissues, is used clinically to delay blood clottingblood clotting,
process by which the blood coagulates to form solid masses, or clots. In minor injuries, small oval bodies called platelets, or thrombocytes, tend to collect and form plugs in blood vessel openings.
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heparin

[′hep·ə·rən]
(biochemistry)
An acid mucopolysaccharide acting as an antithrombin, antithromboplastin, and antiplatelet factor to prolong the clotting time of whole blood; occurs in a variety of tissues, most abundantly in liver.
References in periodicals archive ?
HIT is an immune mediated reaction to heparin and, even though it is considered as unpredictable, some risk factors have been described.
Thus, we would like to introduce a novel procedure for heparin neutralization using polybrene by adapting the whole process so it may be performed rapidly with PT and aPTT tests on the analyzer.
Keep unit stock vials as small as possible to limit the potential of heparin overdoses.
In each case, there was no documented use of heparin preoperatively or intraoperatively, without documentation of incidental exposure to UFH with arterial lines, central venous lines, or cell saver devices.
Yontem ve Gerecler: Lenfoblastlar 0 (heparinsiz), 10 ye 20 U/mL heparin konsantrasyonlanna maruz birakilarak 0, 1 ve 2 saatlerde lenfoblastlarin hucre dongusu oranlari FCM ile Olculdu.
Heparin levels in the plasma were determined using the Chromogenix Coatest Heparin kit as per the manufacturer's specifications.
HIT II has three classifications: isolated HIT with thrombocytopenia only, yet substantial risk of symptomatic and fatal thrombosis; HITT with thrombocytopenia and thrombosis; and rapid onset HIT with thrombocytopenia within 24-48 hours of heparin administration.
In addition, AAJ recently certified a Heparin Litigation Group.
The TGA has been testing heparin products since March 2008.
When the FDA announced in March that the heparinlike contaminant identified in heparin products was OSCS, the agency did not know whether it was related to the adverse events.
In the MedMarx Data Report, heparin was the third most commonly reported drug involved in medication incidents causing harm in the United States (Hicks, Becker, & Cousins, 2006).