hemosiderosis

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hemosiderosis

[‚hē·mō‚sid·ə′rō·səs]
(physiology)
Deposition of hemosiderin in body tissues without tissue damage, reflecting an increase in body iron stores.
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Earlier findings concerning the H63D genotype and the peculiar findings in our case led us to hypothesize about its involvement in the development of massive hepatic hemosiderosis.
I am sure that continued work will help to clarify the genetics of hepatic and systemic iron overload, and I hope that such work will help to explain the finding of hepatic hemosiderosis in patients with liver disease but without the C282Y mutation.
The patient's chemotherapeutic drugs included known hepatotoxins, but her total methotrexate dose was only 450 mg, and the drug combinations in question are commonly received without leading to hepatic cirrhosis or hepatic hemosiderosis.