hepatocyte


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hepatocyte

[hə′pad·ə‚sīt]
(histology)
An epithelial cell constituting the major cell type in the liver.
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Its new cell lines, which consist of both human and animal hepatocytes, are designed for use in a number of in-vitro applications including drug toxicity and metabolism studies, as well as studies into drug-drug interactions and drug-transporter activity.
Hepatoblasts are bipotential liver progenitor cells that can differentiate into either hepatocytes, cells that comprises the majority of liver tissue, or cholangiocytes, epithelial cells of the bile duct.
The report provides comprehensive information on the Hepatocyte Growth Factor (Hepatopoietin-A or Lung Fibroblast Derived Mitogen) , targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.
El Kot21 described similar findings showing hepatocyte degeneration, swelling and apoptosis by using sodium nitrate along with normal diet.
2] either in Lab-Tek chambered slides or in 10 cm dishes (Nalge, Nunc) in the Ham's F-12/Dulbecco's modified Eagle's basal hepatocyte growth medium supplemented with 10% fetal bovine serum.
Evaluations for morphologic and functional characteristics were done on day 28 and for specific hepatocyte markers on days 14 and 28, owing to different expression patterns of the chosen markers.
The data are presented as the mean values [+ or -] standard error of triplicate samples from six independent hepatocyte culture preparations.
The offering will focus on contract services applying the B-CLEAR[R] technology to rat, mouse and Transporter Certified[TM] human hepatocytes.
Washington, July 28 ( ANI ): Researchers transplanted derived functional hepatocytes from human stem cells into mice suffering from acute liver injury, and found that these liver cells functioned normally and raised survival of the treated animals.
Also, ROSU exposure increased the activity of glucose-6-phosphate dehydrogenase with no change in the activity of alkaline phosphatase together with deletion in protein and glycogen hepatocytes content.
The 3 biopsy samples exhibited a pattern of centrilobular injury characterized by ceroidladen macrophages, hepatocyte anisonucleosis, and lipofuscin pigment, as well as centrilobular steatosis.

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