heptad


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heptad

[′hep‚tad]
(science and technology)
A group of seven.
References in periodicals archive ?
Abstract #129 "T-Cells Edited to Express CCR5 or CXCR4 Fused to the C34 Peptide from gp41 Heptad Repeat-2 Exhibit Robust Protection from Diverse HIV-1 Isolates" Wednesday, March 6, 2013 The data demonstrate potent inhibition of HIV infection in cells expressing a chimeric protein comprising a portion of the HIV envelope fused to either the CXCR4 or CCR5 HIV co-receptors.
The S2 subunit, which contains a putative fusion peptide and 2 heptad repeats (HR1 and HR2), is responsible for fusion between the viral and target cell membranes.
The 2- heptad repeats play an essential role in membrane fusion and are able to form trimeric coiled coils (13).