heptad


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heptad

[′hep‚tad]
(science and technology)
A group of seven.
References in periodicals archive ?
Comparison of functional domain of F protein with consensus sequences identified several amino acid substitutions in signal peptide with a single substitution, total of four substitutions in heptad repeat regions (HRa,HRb,HRc) and transmembrane domain had four substitutions.
PCR sequencing with primers Zot F/ctxA R indicated the presence of 4 heptad (TTTTGAT) repeats in the ToxR binding region of ctxAB promoter, similar to El Tor biotype (2).
The fusion peptide region is followed by two heptad repeat sequences of hydrophobic amino acids (N-terminal heptad repeat and C terminal heptad repeat) that form helical domains with hydrophobic faces.
The factors influencing higher genetic diversity at msp-3[alpha] could be: (i) inter-allelic recombination (14); and (ii) presence of polymorphism prone region such as alanine rich heptad repeats.
gp41 is the most conservative region and thus its Heptad Repeat (HR) regions have been targeted for many of new drugs (Qadir & Malik, 2009), an evidence for its conservation.
See other essays in this collection for the history and bibliography about the heptad.
2) Boyce explains that Ahura Mazda forms a heptad with six other Amesha Spentas ("Holy Immortals," including the God of fire, Asha Vahishta) and other lesser Yazata spirits ("Beings worthy of worship").
In the process of fusion, two heptad repeat domains (HRI and HR2) of gp41 form a helical bundle containing trimers of each domain.
NT-proBNP was reported to be a trimer containing a coiled-coil motif of repeating heptad units (7).