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heterophile antibody

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heterophile antibody [′hed·ə·rə‚fīl ′an·ti·bäd·ē]
(immunology)
Substance that will react with heterophile antigen; found in the serum of patients with infectious mononucleosis.
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Laboratory findings Complications Atypical lymphocytosis Sensitive but not specific Positive heterophile antibody Not accurate in young children (Monospot) test High levels of anti-VCA IgM May cross-react with rheumatoid factor Raised liver enzymes (AST, ALT) Sensitive but not specific Specific anti-EBV antibodies are used less frequently for diagnosis of acute IM because the tests are more time-consuming.
Laboratory-based investigations of IM and Epstein-Barr virus by Bennett, Nick / Medical Laboratory Observer
28,29) The diagnosis of EBV hepatitis is suggested by the appropriate clinical symptoms and laboratory findings and confirmed by a positive EBV IgM antibody, monospot, and/or heterophile antibody test.
Epstein Barr virus hepatitis: case series and review by Crum, Nancy F. / Southern Medical Journal
The AxSYM [beta]-human chorionic gonadotropin assay has previously been shown to be subject to heterophile antibody interference in several female patients.
False-positive AxSYM cardiac troponin I results in a 53-year-old ... by Knoblock, Ronald J.; Lehman, Christopher M.; Smith, Ruth A.; Apple, Fred S.; Roberts, William L. / Archives of Pathology & Laboratory Medicine
 
 
 
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