hexokinase


Also found in: Dictionary, Medical, Acronyms, Wikipedia.

hexokinase

[¦hek·sō′kī‚nās]
(biochemistry)
Any enzyme that catalyzes the phosphorylation of hexoses.
References in periodicals archive ?
Reduction in hexokinase II levels results in decreased cardiac function and altered remodeling after ischemia/reperfusion InjuryNovelty and significance.
The activity of hexokinase is remarkably decreased while glucose-6-phosphatase and fructose 1, 6-bisphosphatase are significantly (p < 0.
Sirtuin-3 deacetylation of cyclophilin D induces dissociation of hexokinase II from the mitochondria.
2000) Increased expression of GLUT-4 and hexokinase in rat epitrochlearis muscles exposed to AICAR in vitro.
The discovery of these four catalysts for energy production, called hexokinases, generated more research into how the body metabolizes carbohydrates, and how interfering with those enzymes through medications could help manage metabolic disorders such as diabetes.
Following separation of the plasma -NaF and serum -SST, glucose concentrations were measured in both plasma and serum by an enzymatic hexokinase assay (assay CV [less than or equal to] 5%), using Architect c8000 with automated processing system (Abbott, USA).
Glucose 6 phosphate which is increased because of deficiency of the enzyme inhibits hexokinase enzyme which transforms glucose to glucose 6 phosphate with negative feedback and thus the glycolysis and hexose monophosphate pathway is supressed.
The ATP reacted with glucose in the presence of hexokinase to produce ADP and glucose-6-phosphate (G6P).
The estimations done in the blood samples collected include cytochrome F420 activity, cholesterol oxidase activity--cholesterol ring oxidase activity, cholesterol side chain oxidase activity and cholesterol aromatase activity, digoxin, lactate, pyruvate, ammonia, ATP, glutamate, acetyl CoA, acetyl choline, ALA, homocysteine, cholesterol and bile acid levels as well as cyto C and hexokinase levels activity.
Interestingly, hexokinase mRNA expression was increased 80% by P4 (P<0.
42) Sub-chronic inhalation of FA affects the main metabolic pathways, by which glucose participates in altering the activities of glucose-6-phosphate dehydrogenase (G6PD), lactate dehydrogenase (LDH), malate dehydrogenase (MDH) and hexokinase (HK) enzymes.