hexosaminidase A

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hexosaminidase A

[hek‚säs·ə′min·ə‚dās ′ā]
(biochemistry)
An enzyme which catalyzes the hydrolysis of the N-acetylgalactosamine residue from certain gangliosides.
References in periodicals archive ?
1,5) In Sandhoff's disease, total hexosaminidase activity is reduced to less than 2 - 3% of normal, unlike Tay Sachs, where total hexosaminidase activity is preserved due to functional [beta]-hexosaminidase B activity.
IgE-mediated activation caused a rapid release of [beta]- hexosaminidase in basophilic cells and mast cells (Fig.
A glycine250 to aspartate substitution in the [alpha]-subunit of hexosaminidase A causes juvenile-onset Tay-Sachs disease in a Lebanese-Canadian Family.
M2] gangliosidosis B1 variant: biochemical and molecular characterization of hexosaminidase A.
Expression of hexosaminidase isoenzymes in childhood leukemia.
In preliminary experiments with other lysosomal enzymes, such as hexosaminidase and [beta]-galactosidase, we observed that activities on filter-paper cards were stable over a period of several weeks when stored dry at room temperature.
Detection of heterozygotes and homozygotes by serum hexosaminidase assay.
Standardization of leukocytes for Tay-Sachs hexosaminidase assay [Abstract].
The subunit and polypeptide structure of hexosaminidase from human placenta.